What is a common side effect of Hydrochlorothiazide?

Hydrochlorothiazide is a thiazide diuretic commonly used to manage hypertension and edema. One of its known side effects is dry mouth, which can occur due to a reduction in saliva production. Diuretics like Hydrochlorothiazide work by increasing urine output, which can lead to dehydration or changes in electrolyte balance, thereby affecting salivary gland function and resulting in a sensation of dry mouth.

While headaches, nausea, and palpitations may also occur in some individuals taking Hydrochlorothiazide, they are not as commonly associated with this medication as dry mouth is. Patients may experience headaches due to changes in blood pressure, nausea from electrolyte imbalances, or palpitations as a reaction to fluid depletion, but these effects are typically less prevalent than the experience of dry mouth. Recognizing the common side effects helps in managing patient care, considering hydration and saliva substitutes as potential interventions.