What complication is commonly associated with cyclosporine use after an organ transplant?

Gingival hyperplasia is a well-documented complication associated with the use of cyclosporine, particularly in post-organ transplant patients. Cyclosporine is an immunosuppressive medication that is commonly prescribed to prevent organ rejection after transplantation. While it is effective in this role, it also has several side effects due to its influence on metabolic processes and immune response.

Gingival hyperplasia occurs because cyclosporine causes an increase in fibroblast proliferation and collagen synthesis in the gingival tissues. This leads to an overgrowth of the gums, which can cause discomfort, aesthetic concerns, and difficulties with oral hygiene. Managing this side effect is essential for maintaining oral health and preventing further complications, such as periodontal disease.

Other options present potential complications related to organ transplant medications or conditions, but they are not as directly linked to cyclosporine use as gingival hyperplasia is. Understanding the specific side effects associated with cyclosporine helps clinicians provide better patient care, including counseling on oral hygiene practices and monitoring for signs of gingival overgrowth.